Hydrogen Bromide → 4-(4-Bromo-2-fluorophenylamino)-5-fluoro-6-oxo-1-pyridin-3-ylmethyl-1,6-dihydropyridine-3-carboxylic acid methyl ester
Reaction equation
[Br:24][CH2:25][c:26]1[cH:27][n:28][cH:29][cH:30][cH:31]1.[BrH:23].[CH3:2][O:3][C:4](=[O:5])[c:6]1[cH:7][nH:8][c:9](=[O:22])[c:10]([F:21])[c:11]1[NH:12][c:13]1[c:14]([F:20])[cH:15][c:16]([Br:19])[cH:17][cH:18]1.[LiH:1].[O:32]=[CH:33][N:34]([CH3:35])[CH3:36]>>[CH3:2][O:3][C:4](=[O:5])[c:6]1[cH:7][n:8]([CH2:25][c:26]2[cH:27][n:28][cH:29][cH:30][cH:31]2)[c:9](=[O:22])[c:10]([F:21])[c:11]1[NH:12][c:13]1[c:14]([F:20])[cH:15][c:16]([Br:19])[cH:17][cH:18]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-9230dd53866f4c958d42796a1e9dceb9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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