Phenylboronic Acid → 5-Phenyl-2-furaldehyde

HRID 1909804Notes

Reaction equation

Br[C:2]1[O:6][C:5]([CH:7]=[O:8])=[CH:4][CH:3]=1.[C:9]1(B(O)O)[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1>>[C:9]1([C:2]2[O:6][C:5]([CH:7]=[O:8])=[CH:4][CH:3]=2)[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1

Participants

Reactant 2

HCID 66827Phenylboronic Acid

HCID 6003285-Bromofuran-2-carbaldehyde

Product 1

HCID 27694205-Phenyl-2-furaldehydeYield 101.9%

Procedure

The title compound (2.0 g, 95%) was prepared from 5-bromo-2-furaldehyde (2.0 g, 11.4 mmol) and phenylboronic acid (1.5 g, 12 mmol) using the procedure of Example 159, step 1.

Sources & evidence

ORD record: ord-dc019207049445f290890eceaf3b9049
Source dataset: uspto-grants-2013_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08598359B2

Reaction notes

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