反应详情

To a solution of tert-butyl 4-(1-methyl-1H-imidazol-2-yl)piperidine-1-carboxylate (132 mg) in EtOAc (1.3 ml) was added 4N hydrogen chloride in EtOAc (1.3 ml) and the mixture was stirred at room temperature for 2 hours. Solvent was removed in vacuo to give 4-(1-methyl-1H-imidazol-2-yl)piperidine dihydrochloride (108 mg) as a colorless powder. The obtained crude product was used in next reaction without further purification.

1. customSolvent was removed in vacuo