Hydrogen Peroxide → HCID 178519824, compound

HRID 1911490Notes

Reaction equation

HRID 1911490 reaction equation
Cl[C:2]1[CH:7]=[CH:6][N:5]=[CH:4][C:3]=1[CH:8]=[O:9].[OH:10]O>Cl>[OH:10][C:2]1[CH:7]=[CH:6][N:5]=[CH:4][C:3]=1[CH:8]=[O:9]

Participants

4

Reactant 2

HCID 784Hydrogen PeroxideHCID 140466744-Chloropyridine-3-carbaldehyde

Product 1

HCID 178519824HCID 178519824, compoundYield 80%

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidCatalyst

Procedure

Following the procedure described in MARSAIS et al. (J. Het. Chem., vol. 25, p. 81-87, 1988), compound 2 is heated for 6 h in an aqueous solution of 3 N HCl containing several drops of 3% H2O2, in order to obtain 4-hydroxypyridine-3-carboxaldehyde 4 as a colorless solid (>80%).

Sources & evidence

ORD record
ord-274dcf85de9744c58e635c4b1bd640da
Source dataset
uspto-grants-2013_12
Patent number
US08604063B2

Reaction notes

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