D-(+)-Cellobiose (CNP0226604.15) → (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal

HRID 1912287Notes

Reaction equation

HRID 1912287 reaction equation
O=C[C@@H]([C@H]([C@@H](CO)O)O)O.[CH2:11]([OH:33])[C@H:12]1[O:17][C@@H:16]([O:18][C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)[C@H:15]([OH:30])[C@@H:14]([OH:31])[C@@H:13]1[OH:32]>C(O)C>[O:18]=[CH:16][C@@H:15]([C@H:14]([C@@H:13]([C@@H:12]([CH2:11][OH:33])[OH:17])[OH:32])[OH:31])[OH:30]

Participants

4

Reactant 2

HCID 10712D-(+)-Cellobiose (CNP0226604.15)HCID 644160aldehydo-D-Xylose

Product 1

HCID 107526(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

When evaluated for growth on glucose, xylose, and cellobiose in 250-mL flasks, mutagenized strains 22-1-12 and 14-2-6 achieved the highest ethanol levels, productivities, and fermentation efficiencies on glucose, strains WT-2-1 and 22-1-1 performed slightly better than the other strains on cellobiose, and strains 14-2-6 and 22-1-12 performed best on xylose. However, compared to the results with glucose at 48 h (about 18 g/L ethanol), these strains produced only about 3 g/L with xylose at 96 h. Less than half the consumed xylose was converted to ethanol.

Sources & evidence

ORD record
ord-abcee281556f456f9331bb0c7458df16
Source dataset
uspto-grants-2013_12
Patent number
US08609382B1

Reaction notes

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