反应详情

温度

110 °C

50 g (0.174 mol) phosphorus oxybromide are heated to 65° C., combined with 10 g (0.039 mol) 6-(4-chloro-phenyl)-1H-quinolin-2-one and heated to 110° C. for 3 h. The reaction mixture is then poured onto ice water and made alkaline with ammonia solution. The precipitate is filtered off and dried in the drying cupboard at 60° C.

1. additionThe reaction mixture is then poured onto ice water
2. filtrationThe precipitate is filtered off
3. customdried in the drying cupboard at 60° C.