反应详情

A solution of compound 1 (550 mg) and Et3N (1 mL) in HCO2Et (20 mL) was refluxed for 12 h. The mixture was cooled down and washed with 1 N HCl and sat. NaHCO3. The solvents were removed by evaporation under reduced pressure to give product 14 as solid: 606 mg. The crude product appeared to be pure by TLC and NMR and used for the next step reaction without further purification.

1. temperatureThe mixture was cooled down
2. washwashed with 1 N HCl and sat. NaHCO3
3. customThe solvents were removed by evaporation under reduced pressure