HRID1918123

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID15891

Phenyl carbonochloridate

C7H5ClO2

HCID46196775

3-tert-Butyl-1-(pyridin-3-yl)-1H-pyrazol-5-amine

C12H16N4

PRODUCTS

生成物

结构：CC(C)(C)c1cc(NC(=O)Oc2ccccc2)n(-c2cccnc2)n1

HCID66876858

未命名化合物

收率 95.1%

PROCEDURE

实验过程

Following the procedure in Example 118A, 3-tert-butyl-1-(pyridin-3-yl)-1H-pyrazol-5-amine (665 mg, 3.08 mmol) and phenyl chloroformate (705 mg, 4.5 mmol) were reacted to give phenyl 3-tert-butyl-1-(pyridin-3-yl)-1H-pyrazol-5-ylcarbamate (984 mg, 2.93 mmol, 95%). 1H NMR (300 MHz, DMSO-d6) δ 7.42-7.39 (m, 3H), 7.30-7.26 (m, 5H), 6.85 (t, 1H), 6.82 (d, 2H), 1.21 (s, 9H); LC-MS (ESI) m/z 337 (M+H)+.

WORKUP

后处理

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