Iodoethane → 9-Ethyl-9H-fluorene

HRID 1918425Notes

Reaction equation

[CH:1]1[C:13]2[CH2:12][C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[C:5]=2[CH:4]=[CH:3][CH:2]=1.[Li][CH2:15][CH2:16]CC.ICC>>[CH2:15]([CH:12]1[C:11]2[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=2[C:5]2[C:13]1=[CH:1][CH:2]=[CH:3][CH:4]=2)[CH3:16]

Participants

Reactant 3

HCID 6340Iodoethane

HCID 6853Fluorene

HCID 178418339Butyllithium

Product 1

HCID 168019-Ethyl-9H-fluoreneYield 97.5%

Procedure

Fluorene (5.0 g, 30.1 mmol), n-BuLi (16 ml, 40 mmol, 2.5 M in hexane), RX=iodoethane (7.04 g, 45.1 mmol). 41 was isolated as yellow oil (5.7 g, 97%).

Sources & evidence

ORD record: ord-4d031c84ab044a2f9c5a75a678f3a061
Source dataset: uspto-grants-2013_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08618328B2

Reaction notes

Loading…