HRID1920299

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6397

Chlorotrimethylsilane

C3H9ClSi

HCID28928

Chloro(1,1-dimethylethyl)dimethylsilane

C6H15ClSi

HCID139400

Triisopropylsilyl chloride

C9H21ClSi

HCID12173050

未命名化合物

PRODUCTS

生成物

结构：CC1(C)CCC(=O)/C(=C/O[Si](C)(C)C(C)(C)C)C1

HCID44594327

未命名化合物

$结构：CC(C)[Si](O/C=C1\CC(C)(C)CCC1=O)(C(C)C)C(C)C$

HCID44594328

未命名化合物

HCID44594329

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID8471

Triethylamine

C6H15N

PROCEDURE

实验过程

reacting the (2E)-2-(hydroxymethylene)-4,4-dimethylcyclohexanone, triethylamine and trimethylchlorosilane, tert-butylchlorodimethylsilane, or triisopropylchlorosilane to provide (2E)-4,4-dimethyl-2-(((triisopropylsilyl)oxy)methylene)cyclohexanone, (2E)-4,4-dimethyl-2-(((trimethylsilyl)oxy)methylene)cyclohexanone, or (2E)-2-(((tert-butyl(dimethyl)silyl)oxy)methylene)-4,4-dimethylcyclohexanone and isolating or not isolating the (2E)-4,4-dimethyl-2-(((triisopropylsilyl)oxy)methylene)cyclohexanone, (2E)-4,4-dimethyl-2-(((trimethylsilyl)oxy)methylene)cyclohexanone, or (2E)-2-(((tert-butyl(dimethyl)silyl)oxy)methylene)-4,4-dimethylcyclohexanone;

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-8248d104ef044f67a0803ea61a8338e2
来源数据集: uspto-grants-2012_05
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08168784B2
来源说明: uspto-grants-2012_05

反应 SMILES

[OH:1]/[CH:2]=[C:3]1/[C:4](=[O:11])[CH2:5][CH2:6][C:7]([CH3:10])([CH3:9])[CH2:8]/1.[CH3:12][Si:13]([CH3:16])([CH3:15])Cl.[C:17]([Si:21](Cl)([CH3:23])[CH3:22])([CH3:20])([CH3:19])[CH3:18].[CH:25]([Si:28]([CH:33]([CH3:35])[CH3:34])([CH:30]([CH3:32])[CH3:31])Cl)([CH3:27])[CH3:26]>C(N(CC)CC)C>[CH3:10][C:7]1([CH3:9])[CH2:6][CH2:5][C:4](=[O:11])/[C:3](=[CH:2]/[O:1][Si:28]([CH:33]([CH3:35])[CH3:34])([CH:30]([CH3:32])[CH3:31])[CH:25]([CH3:27])[CH3:26])/[CH2:8]1.[CH3:10][C:7]1([CH3:9])[CH2:6][CH2:5][C:4](=[O:11])/[C:3](=[CH:2]/[O:1][Si:13]([CH3:16])([CH3:15])[CH3:12])/[CH2:8]1.[Si:21]([O:1]/[CH:2]=[C:3]1/[C:4](=[O:11])[CH2:5][CH2:6][C:7]([CH3:9])([CH3:10])[CH2:8]/1)([C:17]([CH3:20])([CH3:19])[CH3:18])([CH3:23])[CH3:22]