Hydrochloric Acid → 1-(4-Benzylpiperazin-1-yl)tetrahydropyrimidin-2(1H)-one

HRID 192114Notes

Reaction equation

HRID 192114 reaction equation
[C:27]([O:28][CH2:29][CH3:30])(=[O:31])[CH3:32].[CH2:13]([c:14]1[cH:15][cH:16][cH:17][cH:18][cH:19]1)[N:20]1[CH2:21][CH2:22][N:23]([NH2:26])[CH2:24][CH2:25]1.[CH3:34][OH:35].[CH3:36][CH2:37][O:38][C:39](=[O:40])[CH3:41].[ClH:33].[O:1]=[CH:2][CH2:3][CH2:4][NH:5][C:6]([O:7][C:8]([CH3:9])([CH3:10])[CH3:11])=[O:12]>>[CH2:2]1[CH2:3][CH2:4][NH:5][C:6](=[O:12])[N:26]1[N:23]1[CH2:22][CH2:21][N:20]([CH2:13][c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)[CH2:25][CH2:24]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 887MethanolHCID 8857Ethyl Acetate2×HCID 10910051tert-Butyl N-(3-oxopropyl)carbamateHCID 121984534-Benzylpiperazin-1-amine

Product 1

HCID 672325181-(4-Benzylpiperazin-1-yl)tetrahydropyrimidin-2(1H)-one

Sources & evidence

ORD record
ord-620d3dfd990b402db1965687d1a7e7be
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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