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HRID1922199

反应详情

EQUATION

反应方程式

HRID 1922199 的结构方程式

REACTANTS

反应物

2
结构：N[C@H]1c2ccccc2C[C@H]1O
HCID9866743

未命名化合物

结构：CNC(=O)c1cc(Oc2ccc3nc(S(C)=O)oc3c2)ccn1
HCID57725414

未命名化合物

PRODUCTS

生成物

1
结构：CNC(=O)c1cc(Oc2ccc3nc(N[C@H]4c5ccccc5C[C@H]4O)oc3c2)ccn1
HCID24821930

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC(=O)N(C)C
溶剂HCID31374

Dimethylacetamide

C4H9NO

PROCEDURE

实验过程

A solution of 4-(2-(methylsulfinyl)benzo[d]oxazol-6-yloxy)-N-methylpyridine-2-carboxamide (17 mg, 0.05 mmol, 1.0 eq) and (1S,2R)-1-amino-2,3-dihydro-1H-inden-2-ol (30 mg, 0.2 mml, 4.0 eq) in 1 mL of N,N-dimethylacetamide was heated in the microwave at 90° C. for 600 seconds. The crude product was purified by reverse phase prep HPLC to give the title compound. MH==417.0.

WORKUP

后处理

  1. customThe crude product was purified by reverse phase prep HPLC