HCID 86649161, compound → HCID 67520595, compound

HRID 1925506Notes

Reaction equation

HRID 1925506 reaction equation
[C:1]12([CH2:11][O:12][C:13]3[CH:18]=[CH:17][C:16]([CH2:19][CH2:20][NH:21]C(=O)OC(C)(C)C)=[CH:15][CH:14]=3)[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2>Cl.CO>[C:1]12([CH2:11][O:12][C:13]3[CH:18]=[CH:17][C:16]([CH2:19][CH2:20][NH2:21])=[CH:15][CH:14]=3)[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2

Participants

4

Reactant 1

HCID 86649161HCID 86649161, compound

Product 1

HCID 67520595HCID 67520595, compoundYield 87.3%

Reagents, catalysts & solvents 2

HCID 313Hydrochloric AcidSolventHCID 887MethanolSolvent

Procedure

Obtained from Intermediate 35 (1.3 g, 3.37 mmol) in hydrogen chloride 1.25M in methanol by the same procedure described in Intermediate 17. The precipitate obtained was separated by filtration giving the title compound as a yellow solid (0.84 g, 87%). MS (M+): 286.

Workup

  1. customThe precipitate obtained
  2. customwas separated by filtration

Sources & evidence

ORD record
ord-6fa4c6590e31404b9d94ef4d00673872
Source dataset
uspto-grants-2012_05
Patent number
US08178679B2

Reaction notes

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