Hydrochloric Acid → HCID 67520630, compound

HRID 1925524Notes

Reaction equation

HRID 1925524 reaction equation
[CH:1]12[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH:2]1[CH2:11][CH2:12][O:13][C:14]1[CH:15]=[C:16]([CH2:20][CH2:21][NH:22]C(=O)OC(C)(C)C)[CH:17]=[CH:18][CH:19]=1)[CH2:8]2.Cl>CO>[CH:3]12[CH2:9][CH:7]3[CH2:6][CH:5]([CH2:10][CH:1]([CH2:8]3)[CH:2]1[CH2:11][CH2:12][O:13][C:14]1[CH:15]=[C:16]([CH2:20][CH2:21][NH2:22])[CH:17]=[CH:18][CH:19]=1)[CH2:4]2

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 86649168HCID 86649168, compound

Product 1

HCID 67520630HCID 67520630, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Obtained from Intermediate 79 (1.25 g, 3.13 mmol) and hydrogen chloride 1.25 M in methanol (40 mL) by the same procedure described in Intermediate 17 (reaction time: overnight). The title compound was obtained as a yellow oil (0.71 g, 76%) and used in the next step without further purification. MS (M+): 300.

Sources & evidence

ORD record
ord-1638c158a15646ddacc84ae7562f4c19
Source dataset
uspto-grants-2012_05
Patent number
US08178679B2

Reaction notes

Loading…