Isopropanol → HCID 66628155, compound

HRID 1926510Notes

Reaction equation

HRID 1926510 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([P:9]([C:12]2[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[CH:14][CH:13]=2)(=[O:11])[OH:10])=[CH:5][CH:4]=1.[OH-].[CH2:21]([N+:25]([CH2:34][CH2:35][CH2:36][CH3:37])([CH2:30][CH2:31][CH2:32][CH3:33])[CH2:26][CH2:27][CH2:28][CH3:29])[CH2:22][CH2:23][CH3:24].CC(O)C>O>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([P:9]([C:12]2[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[CH:14][CH:13]=2)(=[O:10])[O-:11])=[CH:7][CH:8]=1.[CH2:34]([N+:25]([CH2:21][CH2:22][CH2:23][CH3:24])([CH2:26][CH2:27][CH2:28][CH3:29])[CH2:30][CH2:31][CH2:32][CH3:33])[CH2:35][CH2:36][CH3:37]

Participants

5

Reactant 3

HCID 3776IsopropanolHCID 624223Bis(4-methoxyphenyl)phosphinic acidHCID 2723671Tetrabutylammonium Hydroxide

Product 1

HCID 66628155HCID 66628155, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

To a flask were added 2.0 g bis(4-methoxyphenyl)phosphinic acid, 3.0 g of a 55-60% solution of tetrabutylammonium hydroxide in water, 2.0 g of water and 18 ml 2-propanol. After heating to 50 C under nitrogen for 1 hour, the solvent was removed and another 20 ml of 2-propanol were added and removed by distillation under reduced pressure. A waxy solid was obtained.

Workup

  1. temperatureAfter heating to 50 C under nitrogen for 1 hour
  2. customthe solvent was removed
  3. additionanother 20 ml of 2-propanol were added
  4. customremoved by distillation under reduced pressure
  5. customA waxy solid was obtained

Sources & evidence

ORD record
ord-f253c03545cd48278e238ea28105752e
Source dataset
uspto-grants-2012_05
Patent number
US08182718B2

Reaction notes

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