Triethylamine → HCID 44218422, compound

HRID 1928813Notes

Reaction equation

HRID 1928813 reaction equation
[C@H:1]1([NH:10][C:11]2[CH:20]=[CH:19][C:18]3[C:13](=[CH:14][CH:15]=[C:16]([NH2:21])[CH:17]=3)[N:12]=2)[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][CH2:2]1.C(N(CC)CC)C.[C:29](Cl)(=[O:33])[CH:30]([CH3:32])[CH3:31]>C1(C)C=CC=CC=1>[C@H:1]1([NH:10][C:11]2[CH:20]=[CH:19][C:18]3[C:13](=[CH:14][CH:15]=[C:16]([NH:21][C:29](=[O:33])[CH:30]([CH3:32])[CH3:31])[CH:17]=3)[N:12]=2)[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][CH2:2]1

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 62325Isobutyryl chlorideHCID 57860958(R)-N2-Indan-1-yl-quinoline-2,6-diamine

Product 1

HCID 44218422HCID 44218422, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

(R)—N2-indan-1-yl-quinoline-2,6-diamine (0.05 g, 0.18 mmol), triethylamine (0.028 mL, 0.2 mmol) and isobutyryl chloride (0.021 mL, 0.2 mmol) were dissolved in toluene (2.0 mL).

Sources & evidence

ORD record
ord-d926ad58edb3433da47034d98144de42
Source dataset
uspto-grants-2012_05
Patent number
US08183380B2

Reaction notes

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