Isobutyryl chloride → HCID 68913450, compound

HRID 1928815Notes

Reaction equation

HRID 1928815 reaction equation
[C:1](Cl)(=[O:5])[CH:2]([CH3:4])[CH3:3].[CH3:7][O:8][C:9]1[CH:10]=[CH:11][CH:12]=[C:13]2[C:18]=1[CH:17]([NH:19][C:20]1[CH:29]=[CH:28][C:27]3[C:22](=[CH:23][CH:24]=[C:25]([NH2:30])[CH:26]=3)[N:21]=1)[CH2:16][CH2:15][CH2:14]2>C(N(CC)CC)C>[CH3:7][O:8][C:9]1[CH:10]=[CH:11][CH:12]=[C:13]2[C:18]=1[CH:17]([NH:19][C:20]1[CH:29]=[CH:28][C:27]3[C:22](=[CH:23][CH:24]=[C:25]([NH:30][C:1](=[O:5])[CH:2]([CH3:4])[CH3:3])[CH:26]=3)[N:21]=1)[CH2:16][CH2:15][CH2:14]2

Participants

4

Reactant 2

HCID 62325Isobutyryl chlorideHCID 57860959Rac-n2-(8-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-quinoline-2,6-diamine

Product 1

HCID 68913450HCID 68913450, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

The title compound was prepared in accordance with the general method 9 described in example 116 from isobutyryl chloride, triethylamine and rac-N2-(8-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-quinoline-2,6-diamine; MS: m/e=390.3 (M+H+).

Sources & evidence

ORD record
ord-2475d2a0f026439db0bb75c07cebd37e
Source dataset
uspto-grants-2012_05
Patent number
US08183380B2

Reaction notes

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