反应详情

温度

23 °C

A mixture of 4-methoxy-benzofuran-3-one (CAS no: 7169-35-9) (4.9 g, 19 mmol), sodium acetate (3.06 g, 38 mmol) and hydroxylamine hydrochloride (2.58 g, 38 mmol) in ethanol (40 mL) was refluxed for 6 h. Cooled to 23° C., filtered the precipitate off, washed with ethanol and dried in high vacuum to give the title compound as a white solid (5.93 g, 100%); MS: m/e=180.2 (M+H+).

1. temperaturewas refluxed for 6 h
2. filtrationfiltered the precipitate off,
3. washwashed with ethanol
4. customdried in high vacuum