反应详情

The trans-ester 18 (104 g, 359 mmol) is hydrogenated in methanol (1700 ml) with Pd/C in the presence of one equivalent of HCl (431 ml, 359 mmol, 1.25M in MeOH). The mixture is filtered and evaporated. The residue is redissolved in ether and extracted with 1N-NaOH and brine. Evaporation gives a colourless oil.

1. filtrationThe mixture is filtered
2. customevaporated
3. dissolutionThe residue is redissolved in ether
4. extractionextracted with 1N-NaOH and brine
5. customEvaporation
6. customgives a colourless oil