Dimethylformamide → N-[[2'-(t-butoxycarbonyl)biphenyl-4-yl]methyl]phthalimide

HRID 193008Notes

Reaction equation

HRID 193008 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[c:8]1[c:9](-[c:14]2[cH:15][cH:16][c:17]([CH2:20][Br:21])[cH:18][cH:19]2)[cH:10][cH:11][cH:12][cH:13]1.[C:22]1(=[O:32])[c:23]2[c:24]([cH:28][cH:29][cH:30][cH:31]2)[C:25](=[O:27])[NH:26]1.[K:33].[O:34]=[CH:35][N:36]([CH3:37])[CH3:38]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[c:8]1[c:9](-[c:14]2[cH:15][cH:16][c:17]([CH2:20][N:26]3[C:22](=[O:32])[c:23]4[c:24]([cH:28][cH:29][cH:30][cH:31]4)[C:25]3=[O:27])[cH:18][cH:19]2)[cH:10][cH:11][cH:12][cH:13]1

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 6809PhthalimideHCID 5462222PotassiumHCID 9906257tert-Butyl 4'-(bromomethyl)biphenyl-2-carboxylate

Product 1

HCID 10024731N-[[2'-(t-butoxycarbonyl)biphenyl-4-yl]methyl]phthalimide

Sources & evidence

ORD record
ord-9dcf7552ee1a41c09d6bc3acdbb248e7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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