Phosphorus oxychloride → N-(4,6-Dichloropyrido[3,2-d]pyrimidin-2-yl)acetamide

HRID 193011Notes

Reaction equation

HRID 193011 reaction equation
[C:1]([CH3:2])(=[O:3])[NH:4][c:5]1[n:6][cH:7][c:8]2[c:9]([n:10]1)[cH:11][cH:12][c:13]([Cl:15])[n:14]2.[CH:16]([N:17]([CH2:18][CH3:19])[CH:20]([CH3:21])[CH3:22])([CH3:23])[CH3:24].[O:30]1[CH2:31][CH2:32][O:33][CH2:34][CH2:35]1.[P:25]([Cl:26])([Cl:27])([Cl:28])=[O:29]>>[C:1]([CH3:2])(=[O:3])[NH:4][c:5]1[n:6][c:7]([Cl:27])[c:8]2[c:9]([n:10]1)[cH:11][cH:12][c:13]([Cl:15])[n:14]2

Participants

5

Reactant 4

HCID 24813Phosphorus oxychlorideHCID 312751,4-DioxaneHCID 81531DiisopropylethylamineHCID 86630378HCID 86630378, compound

Product 1

HCID 57698319N-(4,6-Dichloropyrido[3,2-d]pyrimidin-2-yl)acetamide

Sources & evidence

ORD record
ord-329cb948a05b4e1298f2ea9247400978
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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