Ethoxalyl chloride → HCID 59333783, compound

HRID 1930705Notes

Reaction equation

HRID 1930705 reaction equation
[O:1]1[CH2:6][CH2:5][C:4](=[O:7])[CH2:3][CH2:2]1.Cl[C:9](=[O:15])[C:10]([O:12][CH2:13][CH3:14])=[O:11]>>[O:15]=[C:9]([CH:3]1[C:4](=[O:7])[CH2:5][CH2:6][O:1][CH2:2]1)[C:10]([O:12][CH2:13][CH3:14])=[O:11]

Participants

3

Reactant 2

HCID 20884Ethoxalyl chlorideHCID 121599Tetrahydro-4H-pyran-4-one

Product 1

HCID 59333783HCID 59333783, compoundYield 19%

Procedure

Ethyl 2-oxo-2-(4-oxotetrahydro-2H-pyran-3-yl)acetate (272 mg, 19%) was synthesised from tetrahydro-4H-pyran-4-one (1 ml, 10.83 mmol) and ethyl 2-chloro-2-oxoacetate (0.808 ml, 7.22 mmol) by the general procedure for the preparation of diketones. MS (ES−) m/z 199.1 (M−H)−

Sources & evidence

ORD record
ord-65f52fdf3681472e8fb31869a3fef975
Source dataset
uspto-grants-2012_05
Patent number
US08188101B2

Reaction notes

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