HCID 86615251, compound → HCID 86615252, compound

HRID 1932312Notes

Reaction equation

HRID 1932312 reaction equation
[Cl:1][C:2]1[C:7]([NH:8]N=C(CC)CC)=[CH:6][CH:5]=[CH:4][N:3]=1>C1(OC2C=CC=CC=2)C=CC=CC=1>[Cl:1][C:2]1[N:3]=[CH:4][CH:5]=[C:6]2[C:5]([CH3:4])=[C:6]([CH2:7][CH3:2])[NH:8][C:7]=12

Participants

3

Reactant 1

HCID 86615251HCID 86615251, compound

Product 1

HCID 86615252HCID 86615252, compoundYield 143.2%

Reagents, catalysts & solvents 1

HCID 7583Diphenyl EtherSolvent

Procedure

A solution of N-(2-chloropyridin-3-yl)-N'-(1-ethylpropylidene)-hydrazine (1.3 g, 6.1 mmol) prepared in Step 2 in diphenyl ether was stirred for 3 hours at 300° C. The reaction mixture was cooled to room temperature and then purified with silica gel column chromatography to give 850 mg of the titled compound as a pale yellow solid. (Yield: 72%).

Workup

  1. custompurified with silica gel column chromatography

Sources & evidence

ORD record
ord-e6e816601a2a4b0aa856a4ce31d6e0fc
Source dataset
uspto-grants-2012_05
Patent number
US08188114B2

Reaction notes

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