Hydrochloric Acid → HCID 67142726, compound

HRID 1932409Notes

Reaction equation

HRID 1932409 reaction equation
[CH2:1]([N:8]1[C:12]2=[C:13]([NH:19][CH2:20][C:21]3[CH:26]=[CH:25][C:24]([F:27])=[CH:23][CH:22]=3)[N:14]=[C:15]([C:17]#[N:18])[CH:16]=[C:11]2[C:10]([CH3:28])=[C:9]1[CH3:29])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[ClH:30]>C(OCC)(=O)C>[ClH:30].[CH2:1]([N:8]1[C:12]2=[C:13]([NH:19][CH2:20][C:21]3[CH:22]=[CH:23][C:24]([F:27])=[CH:25][CH:26]=3)[N:14]=[C:15]([C:17]#[N:18])[CH:16]=[C:11]2[C:10]([CH3:28])=[C:9]1[CH3:29])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 67141255HCID 67141255, compound

Product 1

HCID 67142726HCID 67142726, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

A solution of 1-benzyl-7-(4-fluorobenzylamino)-2,3-dimethyl-1H-pyrrolo[2,3-c]pyridin-5-carbonitrile prepared in Step 1 in ethyl acetate was saturated with hydrochloric acid gas and then filtered to give 12.0 mg of the titled compound as a white solid.

Workup

  1. filtrationfiltered

Sources & evidence

ORD record
ord-0f7d127dd07d48cbba757ed683b418f9
Source dataset
uspto-grants-2012_05
Patent number
US08188114B2

Reaction notes

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