Hydrochloric Acid → HCID 67143055, compound

HRID 1932412Notes

Reaction equation

HRID 1932412 reaction equation
[F:1][C:2]1[CH:22]=[CH:21][C:5]([CH2:6][NH:7][C:8]2[N:9]=[C:10]([C:19]#[N:20])[CH:11]=[C:12]3[C:16]([CH3:17])=[C:15]([CH3:18])[NH:14][C:13]=23)=[CH:4][CH:3]=1.[ClH:23]>C(OCC)(=O)C>[ClH:23].[F:1][C:2]1[CH:22]=[CH:21][C:5]([CH2:6][NH:7][C:8]2[N:9]=[C:10]([C:19]#[N:20])[CH:11]=[C:12]3[C:16]([CH3:17])=[C:15]([CH3:18])[NH:14][C:13]=23)=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 67142016HCID 67142016, compound

Product 1

HCID 67143055HCID 67143055, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

A solution of 7-(4-fluorobenzylamino)-2,3-dimethyl-1H-pyrrolo[2,3-c]pyridin-5-carbonitrile prepared in Step 1 in ethyl acetate was saturated with hydrochloric acid gas and then filtered to give 3.2 mg of the titled compound as a white solid.

Workup

  1. filtrationfiltered

Sources & evidence

ORD record
ord-2d49d2616aa04a76b03adf48d7300d60
Source dataset
uspto-grants-2012_05
Patent number
US08188114B2

Reaction notes

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