Bromobenzene → 5-(3-fluoro-4-(3-iodo-1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridin-4-yloxy)phenyl)-3-methyl-2-(phenylamino)pyrimidin-4(3H)-one
Reaction equation
[Br:53][c:54]1[cH:55][cH:56][cH:57][cH:58][cH:59]1.[CH3:44][N:45]([c:46]1[cH:47][cH:48][n:49][cH:50][cH:51]1)[CH3:52].[Cl:24][c:25]1[c:26]2[c:27]([n:28][cH:29][cH:30]1)[n:31]([CH2:35][c:36]1[cH:37][cH:38][c:39]([O:42][CH3:43])[cH:40][cH:41]1)[n:32][c:33]2[I:34].[F:1][c:2]1[cH:3][c:4](-[c:9]2[c:10](=[O:23])[n:11]([CH3:22])[c:12]([NH:15][c:16]3[cH:17][cH:18][cH:19][cH:20][cH:21]3)[n:13][cH:14]2)[cH:5][cH:6][c:7]1[OH:8]>>[F:1][c:2]1[cH:3][c:4](-[c:9]2[c:10](=[O:23])[n:11]([CH3:22])[c:12]([NH:15][c:16]3[cH:17][cH:18][cH:19][cH:20][cH:21]3)[n:13][cH:14]2)[cH:5][cH:6][c:7]1[O:8][c:25]1[c:26]2[c:27]([n:28][cH:29][cH:30]1)[n:31]([CH2:35][c:36]1[cH:37][cH:38][c:39]([O:42][CH3:43])[cH:40][cH:41]1)[n:32][c:33]2[I:34]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-5ff4b6f7fc354c94b8e19129f8a0fba9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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