反应详情

2, 4-Dichloro-5,6,7,8-tetrahydroquinazoline (4 g) is dissolved in 50 mL of methylene chloride and the resulting solution covered with 9% NH4OH in saturated brine. Zinc (4 g) is added and the resulting mixture gently refluxed overnight. After filtration through celite, the organic layer is washed with water, dried and concentrated.

1. customthe resulting mixture gently refluxed overnight
2. filtrationAfter filtration through celite
3. washthe organic layer is washed with water
4. customdried
5. concentrationconcentrated