HRID1935378

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6456

Trityl chloride

C19H15Cl

HCID24758

Sodium hydride

HNa

结构：Br.Br.Cc1ccc(S(=O)(=O)N2CCNCCNCC2)cc1

HCID68858021

未命名化合物

PRODUCTS

生成物

结构：Cc1ccc(S(=O)(=O)N2CCNCCN(C(c3ccccc3)(c3ccccc3)c3ccccc3)CC2)cc1

HCID22889150

未命名化合物

PROCEDURE

实验过程

From N-(p-toluenesulfonyl-1,4,7-triazacyclononane dihydrobromide (1.3.13.30), sodium hydride and trityl chloride.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-66f974dfcc67431091f824aaf7d8f924
来源数据集: uspto-grants-2002_05
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06387891B2
来源说明: uspto-grants-2002_05

反应 SMILES

Br.Br.[C:3]1([CH3:21])[CH:8]=[CH:7][C:6]([S:9]([N:12]2[CH2:20][CH2:19][NH:18][CH2:17][CH2:16][NH:15][CH2:14][CH2:13]2)(=[O:11])=[O:10])=[CH:5][CH:4]=1.[H-].[Na+].[C:24](Cl)([C:37]1[CH:42]=[CH:41][CH:40]=[CH:39][CH:38]=1)([C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1)[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>>[C:3]1([CH3:21])[CH:4]=[CH:5][C:6]([S:9]([N:12]2[CH2:13][CH2:14][NH:15][CH2:16][CH2:17][N:18]([C:24]([C:25]3[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=3)([C:37]3[CH:38]=[CH:39][CH:40]=[CH:41][CH:42]=3)[C:31]3[CH:32]=[CH:33][CH:34]=[CH:35][CH:36]=3)[CH2:19][CH2:20]2)(=[O:10])=[O:11])=[CH:7][CH:8]=1