Hydrochloric Acid → HCID 22464539, compound

HRID 1935452Notes

Reaction equation

HRID 1935452 reaction equation
C([NH:8][CH2:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[S:16]([CH2:19][C:20]([F:23])([F:22])[F:21])(=[O:18])=[O:17])(OC(C)(C)C)=O.[ClH:24]>O1CCOCC1>[ClH:24].[F:23][C:20]([F:21])([F:22])[CH2:19][S:16]([C:11]1[CH:12]=[CH:13][CH:14]=[CH:15][C:10]=1[CH2:9][NH2:8])(=[O:18])=[O:17]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 22464486HCID 22464486, compound

Product 1

HCID 22464539HCID 22464539, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent2×

Procedure

To a stirred solution of N-Boc-2-(2,2,2-trifluoroethylsulfonyl)benzylamine (480 mg) in dioxane (4.0 mL) at room temperature was added excess 4.0 M HCl in dioxane. The mixture was stirred until no starting material remained by TLC and was then concentrated in vacuo to afford the title compound as an off-white solid:

Workup

  1. concentrationwas then concentrated in vacuo

Sources & evidence

ORD record
ord-dbc7cc15fc644a0dba20bf2f118640ba
Source dataset
uspto-grants-2002_05
Patent number
US06387911B1

Reaction notes

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