Benzaldehyde → 2-Benzylidene-1-indanone

HRID 1935731Notes

Reaction equation

HRID 1935731 reaction equation
[C:1]1(=[O:10])[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][CH2:2]1.[CH:11](=O)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1.[OH-].[Na+]>CO>[CH:11](=[C:2]1[CH2:3][C:4]2[C:9](=[CH:8][CH:7]=[CH:6][CH:5]=2)[C:1]1=[O:10])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

Participants

5

Reactant 3

HCID 240BenzaldehydeHCID 67351-IndanoneHCID 14798Sodium Hydroxide

Product 1

HCID 2888762-Benzylidene-1-indanone

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a solution of 1-indanone (5.0 g) and benzaldehyde (4.1 g) in methanol (40 ml), was added 2.2 ml of 48% aqueous sodium hydroxide solution. The reaction mixture was stirred at room temperature for 0.5 hr. The resulting precipitate was filtered and washed with water. The yield was 7.9 g.

Workup

  1. filtrationThe resulting precipitate was filtered
  2. washwashed with water

Sources & evidence

ORD record
ord-e299c80eba01428bad09ea6dccf1ec79
Source dataset
uspto-grants-2002_05
Patent number
US06388090B2

Reaction notes

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