Phosgene → HCID 22463382, 화합물

HRID 1937059노트

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HRID 1937059 반응식
C(OCC(C)C)=C.C(Cl)(Cl)=O.[CH2:12]([OH:16])[CH:13]([CH3:15])[CH3:14].C(O[CH:22]=[CH:23][C:24]([O:26][CH2:27][CH:28]([CH3:30])[CH3:29])=[O:25])C(C)C>>[CH2:12]([O:16][C:23](=[CH2:22])[C:24]([O:26][CH2:27][CH:28]([CH3:30])[CH3:29])=[O:25])[CH:13]([CH3:15])[CH3:14]

참가 물질

5

반응물 4

HCID 6371Phosgene2회HCID 6560IsobutanolHCID 7992Vinyl isobutyl etherHCID 56981813Isobutyl 3-isobutoxyacrylate

생성물 1

HCID 22463382HCID 22463382, 화합물

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온도
52.5 °C

실험 절차

100 g (1.0 mol) of isobutyl vinyl ether are initially charged in a 500 ml stirred apparatus and heated to 50-55° C. 113 g (1.15 mol) of phosgene are subsequently introduced over a period of 11 h. After an extra reaction time of 1.5 h, the reaction mixture is stripped phosgene free at 50-55° C. by introduction of nitrogen. The mixture is subsequently allowed to cool to room temperature, and and [sic] 60.7 g (0.82 mol) of isobutanol are added dropwise. After the addition has ended, the resulting reaction mixture is rectified. This gives 150.4 g (75%) of isobutyl 3-isobutoxyacrylate of b.p. 97° C. at 2.5 mbar.

후처리

  1. customAfter an extra reaction time of 1.5 h
  2. customat 50-55° C.
  3. temperatureto cool to room temperature
  4. additionAfter the addition
  5. customthe resulting reaction mixture

출처 및 근거

ORD 기록
ord-5d79271e136a4d51aa31f26724da04dc
출처 데이터셋
uspto-grants-2002_05
특허 번호
US06392058B1

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