Piperidine → HCID 178431711, compound

HRID 1937885Notes

Reaction equation

HRID 1937885 reaction equation
C1CCNCC1.CC1(C)OC(=O)C(Oc2ccc(Br)cn2)=C1c1ccc(S(C)(=O)=O)cc1>C1COCCO1.CC(C)Oc1cccc(OC(C)C)c1-c1ccccc1P(C1CCCCC1)C1CCCCC1.C[Si](C)(C)[N-][Si](C)(C)C.Nc1ccccc1-c1[c-]cccc1.[Cl][Pd+].[Li+]>CC1(C)OC(=O)C(Oc2ccc(N3CCCCC3)cn2)=C1c1ccc(S(C)(=O)=O)cc1

Participants

6

Reactant 2

HCID 8082PiperidineHCID 99328283-((5-Bromopyridin-2-yl)oxy)-5,5-dimethyl-4-(4-(methylsulfonyl)phenyl)furan-2(5H)-one

Product 1

HCID 178431711HCID 178431711, compoundYield 8%

Reagents, catalysts & solvents 3

HCID 2733832Lithium HexamethyldisilazideReagentHCID 771465301375325-68-0CatalystHCID 312751,4-DioxaneSolvent2×

Conditions

Temperature
80 °C

Workup

  1. additionNo procedure recorded

Sources & evidence

ORD record
ord-849e255008b840f7a2fb7bea4c9a00aa
Source dataset
Pd_CN_Coupling_Informer_Library
Original link
View source

Reaction notes

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