Piperidine → HCID 178525540, compound

HRID 1937889Notes

Reaction equation

HRID 1937889 reaction equation
C1CCNCC1.O=C(O)C[C@H]1CCc2c1n(Cc1ccc(Cl)cc1)c1c(Br)cc(F)cc21>C1COCCO1.CC(C)Oc1cccc(OC(C)C)c1-c1ccccc1P(C1CCCCC1)C1CCCCC1.C[Si](C)(C)[N-][Si](C)(C)C.Nc1ccccc1-c1[c-]cccc1.[Cl][Pd+].[Li+]>O=C(O)C[C@H]1CCc2c1n(Cc1ccc(Cl)cc1)c1c(N3CCCCC3)cc(F)cc21

Participants

6

Reactant 2

HCID 8082PiperidineHCID 11597294(R)-2-(5-broMo-4-(4-chlorobenzyl)-7-fluoro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid

Product 1

HCID 178525540HCID 178525540, compoundYield 0%

Reagents, catalysts & solvents 3

HCID 2733832Lithium HexamethyldisilazideReagentHCID 771465301375325-68-0CatalystHCID 312751,4-DioxaneSolvent2×

Conditions

Temperature
80 °C

Workup

  1. additionNo procedure recorded

Sources & evidence

ORD record
ord-88a735e5af2745379be03451d94accfa
Source dataset
Pd_CN_Coupling_Informer_Library
Original link
View source

Reaction notes

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