Piperidine → HCID 178501343, compound

HRID 1937908Notes

Reaction equation

HRID 1937908 reaction equation
C1CCNCC1.COC(=O)[C@@H]1C[C@@H](OC(=O)N2Cc3cccc(Br)c3C2)CN1C(=O)OCc1ccccc1>CC(C)(C)O.CC(C)Oc1cccc(OC(C)C)c1-c1ccccc1P(C1CCCCC1)C1CCCCC1.Nc1ccccc1-c1[c-]cccc1.O=C([O-])[O-].[Cl][Pd+].[K+].[K+]>COC(=O)[C@@H]1C[C@@H](OC(=O)N2Cc3cccc(N4CCCCC4)c3C2)CN1C(=O)OCc1ccccc1

Participants

6

Reactant 2

HCID 8082PiperidineHCID 547543691-Benzyl 2-methyl (2S,4R)-4-((4-bromoisoindoline-2-carbonyl)oxy)pyrrolidine-1,2-dicarboxylate

Product 1

HCID 178501343HCID 178501343, compoundYield 10%

Reagents, catalysts & solvents 3

HCID 11430Potassium CarbonateReagentHCID 771465301375325-68-0CatalystHCID 6386tert-ButanolSolvent2×

Conditions

Temperature
80 °C

Workup

  1. additionNo procedure recorded

Sources & evidence

ORD record
ord-860c481f61e34acebd358967377af557
Source dataset
Pd_CN_Coupling_Informer_Library
Original link
View source

Reaction notes

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