Piperidine → HCID 178462864, compound

HRID 1937912Notes

Reaction equation

HRID 1937912 reaction equation
C1CCNCC1.CCn1c(=O)c2c(nc(N[C@H]3CCC[C@H]3O)n2Cc2ccc(OC)c(Br)c2)n(CCO)c1=O>CC(C)(C)O.CC(C)Oc1cccc(OC(C)C)c1-c1ccccc1P(C1CCCCC1)C1CCCCC1.Nc1ccccc1-c1[c-]cccc1.O=C([O-])[O-].[Cl][Pd+].[K+].[K+]>CCn1c(=O)c2c(nc(N[C@H]3CCC[C@H]3O)n2Cc2ccc(OC)c(N3CCCCC3)c2)n(CCO)c1=O

Participants

6

Reactant 2

HCID 8082PiperidineHCID 129360362HCID 129360362, compound

Product 1

HCID 178462864HCID 178462864, compoundYield 4%

Reagents, catalysts & solvents 3

HCID 11430Potassium CarbonateReagentHCID 771465301375325-68-0CatalystHCID 6386tert-ButanolSolvent2×

Conditions

Temperature
80 °C

Workup

  1. additionNo procedure recorded

Sources & evidence

ORD record
ord-585b2c8d1ea649a3a6fdfba926e17d7a
Source dataset
Pd_CN_Coupling_Informer_Library
Original link
View source

Reaction notes

Loading…