反应详情

(60 g (0.3 mol) of 4-hydroxybenzophenone, 42 g of benzyl chloride, 45.6 g of potassium carbonate, 0.5 g of potassium iodide and 1 litre of dimethylformamide are introduced into a flask. Stirring is carried out at room temperature for 72 hours. The mixture is filtered and concentrated to dryness without exceeding 30° C. The residue is taken up in methylene chloride and washed with a 10% sodium carbonate solution and then with a saturated lithium chloride solution. The mixture is dried over sodium sulphate and concentrated to dryness. There are obtained 85 g of 4-benzyloxybenzophenone. Yield: 99%.

1. filtrationThe mixture is filtered
2. concentrationconcentrated to dryness
3. customwithout exceeding 30° C
4. washwashed with a 10% sodium carbonate solution
5. dry with materialThe mixture is dried over sodium sulphate
6. concentrationconcentrated to dryness