反应详情

To the solution of 4-chloroacetylcatechol (25 g) in DMF (200 ml) was added sodium azide (10.5 g), and the mixture was stirred at room temperature for 1 hour. The reaction mixture was diluted with ethyl acetate, washed with water and dried over anhydrous magnesium sulfate. After the solvent was evaporated, the solids thus obtained was washed with a solution of n-hexane:ether=5:1 to give 23.2 g of 4-azidoacetylcatechol (yield, 90%).

1. washwashed with water
2. dry with materialdried over anhydrous magnesium sulfate
3. customAfter the solvent was evaporated
4. customthe solids thus obtained
5. washwas washed with a solution of n-hexane