Imidazole → Creatine

HRID 1940468Notes

Reaction equation

HRID 1940468 reaction equation
[NH:1]1C=C[N:3]=[CH:2]1.O=C[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O.[C:18]([NH:21][C@H:22]([C:25]([OH:27])=[O:26])CS)(=O)C>>[O:26]=[C:25]([CH2:22][N:21]([C:2](=[NH:1])[NH2:3])[CH3:18])[OH:27]

Participants

4

Reactant 3

HCID 795ImidazoleHCID 12035N-Acetyl-L-CysteineHCID 107526(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal

Product 1

HCID 586Creatine

Procedure

A creatine kinase buffer solution was prepared to contain 118.9 mmol/L of imidazole (molecular weight 68.1) (Calbiochem, San Diego, Calif.), 11.89 mmol/L of Mg Acetate(H2O)4 (mol. wt. 214.5) (J. T. Baker, Inc.), 23.8 mmol/L of D-Glucose (mol wt 180.2) (Pfanstiehl Labs, Inc.), and 23.77 mmol/L of N-acetyl-L-cysteine (mol wt 163.2) (Boehringer Mannheim Biochemicals, Indianapolis, Ind.).

Sources & evidence

ORD record
ord-8df72c79b62b4f7cabe96186bb6cf4f9
Source dataset
uspto-grants-1997_12
Patent number
US05700653

Reaction notes

Loading…