Cesium carbonate → HCID 15341379, compound

HRID 1940580Notes

Reaction equation

HRID 1940580 reaction equation
[O:1]1[C:6]2[CH:7]=[CH:8][C:9]([C:11]3[C:16]([C:17]([O:19][CH2:20][CH3:21])=[O:18])=[C:15](Cl)[N:14]=[C:13]4[C:23]5[CH:29]=[CH:28][CH:27]=[CH:26][C:24]=5[O:25][C:12]=34)=[CH:10][C:5]=2[O:4][CH2:3][CH2:2]1.C(=O)([O-])[O-].[Cs+].[Cs+].[CH2:36]1[O:44][C:43]2[CH:42]=[CH:41][C:40]([OH:45])=[CH:39][C:38]=2[O:37]1>CN(C=O)C.ClCCl>[O:1]1[C:6]2[CH:7]=[CH:8][C:9]([C:11]3[C:16]([C:17]([O:19][CH2:20][CH3:21])=[O:18])=[C:15]([O:45][C:40]4[CH:41]=[CH:42][C:43]5[O:44][CH2:36][O:37][C:38]=5[CH:39]=4)[N:14]=[C:13]4[C:23]5[CH:29]=[CH:28][CH:27]=[CH:26][C:24]=5[O:25][C:12]=34)=[CH:10][C:5]=2[O:4][CH2:3][CH2:2]1

Participants

6

Reactant 3

HCID 10796Cesium carbonateHCID 68289SesamolHCID 21462919HCID 21462919, compound

Product 1

HCID 15341379HCID 15341379, compound

Reagents, catalysts & solvents 2

HCID 6228DimethylformamideSolventHCID 6344DichloromethaneSolvent

Procedure

A solution of 3.8 g of ethyl 4-(1,4-benzodioxan-6-yl)-2-chlorobenzofuro[3,2-b]pyridine-3-carboxylate and 3.1 g of caesium carbonate in 40 ml of DMF is treated with a solution of 1.7 g of 3,4-methylenedioxyphenol in 20 ml of dichloromethane and stirred overnight. The mixture is worked up in the customary manner and ethyl 4-(1,4-benzodioxan-6-yl)-2-(3,4-methylenedioxyphenoxy)benzofuro[3,2-b]pyridine-3-carboxylate is obtained.

Sources & evidence

ORD record
ord-3ad438d9867f4edfb9cfc41eacb51de7
Source dataset
uspto-grants-1997_12
Patent number
US05700807

Reaction notes

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