反应详情

A mixture of 3-amino-4-hydroxybenzonitrile (50 mg, 0.37 mmol) and potassium O-ethyl-xanthate (65 mg, 0.41 mmol) in pyridine (0.75 mL) was heated at reflux for 2 h. After cooling, the mixture was poured into ice-water. Then concentrated hydrochloric acid (0.2 mL) was added. The solid was collected, washed with water and dried to give 2-thioxo-2,3-dihydrobenzooxazole-5-carbonitrile 30 mg (46%).

1. temperaturewas heated
2. temperatureat reflux for 2 h
3. temperatureAfter cooling
4. customThe solid was collected
5. washwashed with water
6. customdried