huagongshe.com
HRID1945050

反应详情

EQUATION

反应方程式

HRID 1945050 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)C(F)(F)F
HCID6422

未命名化合物

结构：CCOC(=O)[C@H](C)C[C@@H](C)NC(=O)OC(C)(C)C
HCID86648195

未命名化合物

PRODUCTS

生成物

1
结构：CCOC(=O)[C@H](C)C[C@@H](C)N.O=C(O)C(F)(F)F
HCID86648194

未命名化合物

PROCEDURE

实验过程

Next, (2R,4R)-4-tert-butoxycarbonylamino-2-methyl-pentanoic acid ethyl ester (142 mg, 0.548 mmol) is added to trifluoroacetic acid (5 mL). After 10 minutes, the solvent is removed under reduced pressure. Methylene chloride is added and the solvent is removed under reduced pressure to give (2R,4R)-4-amino-2-methyl-pentanoic acid ethyl ester trifluoroacetate. This material is used directly in the subsequent coupling reaction.

WORKUP

后处理

  1. customthe solvent is removed under reduced pressure
  2. additionMethylene chloride is added
  3. customthe solvent is removed under reduced pressure