Hydrochloric Acid → HCID 66995605, compound

HRID 1945201Notes

Reaction equation

HRID 1945201 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([O:20][CH3:21])=[C:6]([S:8][C:9]2[CH:19]=[CH:18][C:12]([C:13]([O:15]CC)=[O:14])=[CH:11][CH:10]=2)[CH:7]=1.[OH-].[Li+].Cl>CO.O>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([O:20][CH3:21])=[C:6]([S:8][C:9]2[CH:19]=[CH:18][C:12]([C:13]([OH:15])=[O:14])=[CH:11][CH:10]=2)[CH:7]=1

Participants

6

Reactant 3

HCID 313Hydrochloric AcidHCID 3939Lithium HydroxideHCID 66996055HCID 66996055, compound

Product 1

HCID 66995605HCID 66995605, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 962WaterSolvent

Procedure

A mixture of the product from step (i) (0.24 g), lithium hydroxide (0.036 g) in methanol (30 ml) and water (5 ml) was stirred at RT overnight then acidified with 2M hydrochloric acid. The mixture was extracted with ethylacetate, the organics dried and evaporated under reduced pressure, yield 0.23 g

Workup

  1. extractionThe mixture was extracted with ethylacetate
  2. customthe organics dried
  3. customevaporated under reduced pressure, yield 0.23 g

Sources & evidence

ORD record
ord-06e74d64edf34435ae84a3f3affbf9cb
Source dataset
uspto-grants-2013_03
Patent number
US08394986B2

Reaction notes

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