HCID 66995743, compound → HCID 66995495, compound

HRID 1945212Notes

Reaction equation

HRID 1945212 reaction equation
C([O:8][C:9]1[CH:21]=[C:20]([Cl:22])[CH:19]=[CH:18][C:10]=1[O:11][C:12]([CH3:17])([CH3:16])[C:13]([OH:15])=[O:14])C1C=CC=CC=1>C(OC(=O)C)C.[Pd]>[Cl:22][C:20]1[CH:19]=[CH:18][C:10]([O:11][C:12]([CH3:17])([CH3:16])[C:13]([OH:15])=[O:14])=[C:9]([OH:8])[CH:21]=1

Participants

4

Reactant 1

HCID 66995743HCID 66995743, compound

Product 1

HCID 66995495HCID 66995495, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8857Ethyl AcetateSolvent

Procedure

A mixture of the product from step (ii) (1.4 g) and 10% Pd/C (0.14 g) in ethylacetate (30 ml) was hydrogenated at 2 Bar for 3 h then filtered through celite. The filtrate was evaporated under reduced pressure, yield 0.6 g.

Workup

  1. filtrationthen filtered through celite
  2. customThe filtrate was evaporated under reduced pressure, yield 0.6 g

Sources & evidence

ORD record
ord-7598a5b132ae4793ba6b217f19d2831d
Source dataset
uspto-grants-2013_03
Patent number
US08394986B2

Reaction notes

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