Indole → (4-Indol-1-yl-pyrimidin-2-yl)-(2,2,6,6-tetramethyl-piperidin-4-yl)-amine

HRID 194928Notes

Reaction equation

HRID 194928 reaction equation
[CH2:30]([O:31][C:32](=[O:33])[CH3:34])[CH3:35].[Cl:1][c:2]1[n:3][c:4]([NH:8][CH:9]2[CH2:10][C:11]([CH3:17])([CH3:18])[NH:12][C:13]([CH3:15])([CH3:16])[CH2:14]2)[n:5][cH:6][cH:7]1.[K+:29].[OH-:28].[nH:19]1[cH:20][cH:21][c:22]2[cH:23][cH:24][cH:25][cH:26][c:27]12>>[c:2]1(-[n:19]2[cH:20][cH:21][c:22]3[cH:23][cH:24][cH:25][cH:26][c:27]23)[n:3][c:4]([NH:8][CH:9]2[CH2:10][C:11]([CH3:17])([CH3:18])[NH:12][C:13]([CH3:15])([CH3:16])[CH2:14]2)[n:5][cH:6][cH:7]1

Participants

6

Reactant 5

HCID 798IndoleHCID 813Potassium CationHCID 961HydroxideHCID 8857Ethyl AcetateHCID 57936167(4-Chloro-pyrimidin-2-yl)(2,2,6,6-tetramethyl-piperidin-4-yl)-amine

Product 1

HCID 57936162(4-Indol-1-yl-pyrimidin-2-yl)-(2,2,6,6-tetramethyl-piperidin-4-yl)-amine

Sources & evidence

ORD record
ord-d27ea5ff63374314988f4f2421249c4b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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