Potassium Bromide → HCID 46205398, compound

HRID 1951326Notes

Reaction equation

[CH2:1]([O:3][CH:4]([O:19][CH2:20][CH3:21])[C:5]1[N:6]=[C:7]2[C:12]([C:13](OCC)=[O:14])=[CH:11][CH:10]=[CH:9][N:8]2[CH:18]=1)[CH3:2].[K+].[Br-]>>[CH2:1]([O:3][CH:4]([O:19][CH2:20][CH3:21])[C:5]1[N:6]=[C:7]2[C:12]([CH2:13][OH:14])=[CH:11][CH:10]=[CH:9][N:8]2[CH:18]=1)[CH3:2]

Participants

Reactant 2

HCID 253877Potassium Bromide

HCID 46205077HCID 46205077, compound

Product 1

HCID 46205398HCID 46205398, compound

Procedure

From 2i (yield: 60%); mp 87-89° C.; IR (KBr) 2977, 1148 cm−1; 1H NMR (400 MHz, CDCl3) δ 1.25 (t, 6H, J=7 Hz), 3.68 (m, 4H), 4.52 (brs, 1H), 5.02 (s, 2H), 5.71 (s, 1H), 6.75 (t, 1H, J=7 Hz), 7.12 (d, 1H, J=7 Hz), 7.65 (s, 1H), 8.00 (d, 1H, J=7 Hz); 13C NMR (100 MHz, CDCl3) δ 15.3, 61.7, 61.9, 98.6, 106.1, 110.7, 112.5, 121.5, 124.8, 130.2, 143.9; MS m/z 250 (M+, 4), 206 (33), 177 (100), 175 (38), 159 (91), 78 (15).

Sources & evidence

ORD record: ord-18fb4bfd20d2455c884d2d61672f5bdc
Source dataset: uspto-grants-2013_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08404707B2

Reaction notes

Loading…