Potassium Bromide → HCID 67360692, compound

HRID 1951359Notes

Reaction equation

[C:1]([C:7]1[C:8]2[N:9]([CH:19]=[C:20]([CH3:22])[N:21]=2)[CH:10]=[CH:11][C:12]=1[NH:13]C(=O)OCC)#[C:2][CH2:3][CH2:4][CH2:5][CH3:6].[K+].[Br-]>>[CH2:3]([C:2]1[N:13]=[C:12]2[C:7](=[C:8]3[N:21]=[C:20]([CH3:22])[CH2:19][N:9]3[CH:10]=[CH:11]2)[CH:1]=1)[CH2:4][CH2:5][CH3:6]

Participants

Reactant 2

HCID 253877Potassium Bromide

HCID 86640850HCID 86640850, compound

Product 1

HCID 67360692HCID 67360692, compound

Procedure

From 25c (yield: 55%); mp 162° C.; IR (KBr) 3061, 2924, 1637, 1528 cm−1; 1H NMR (400 MHz, CDCl3) δ 0.82 (t, 3H, J=7.6 Hz), 1.28 (m, 2H), 1.60 (m, 2H), 2.43 (s, 3H), 2.69 (t, 2H, J=7.6 Hz), 6.56 (s, 1H), 6.82 (d, 1H, J=7.1 Hz), 7.20 (s, 1H), 7.62 (d, 1H, J=7.1 Hz), 10.37 (s, 1H); 13C NMR (100 MHz, CDCl3) δ 13.8, 14.2, 22.3, 27.8, 31.5, 98.8, 101.2, 108.9, 114.1, 118.8, 130.4, 139.1, 139.8, 142.0. Anal. Calcd for C14H17N3: C, 73.98; H, 7.54; N, 18.49. Found: C, 74.05; H, 7.51; N, 18.29.

Sources & evidence

ORD record: ord-9f5498933daa43178e9e2ae08368cd06
Source dataset: uspto-grants-2013_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08404707B2

Reaction notes

Loading…