Hydrochloric Acid → HCID 88176311, compound

HRID 1952795Notes

Reaction equation

HRID 1952795 reaction equation
[ClH:1].[CH3:2][N:3]([CH3:37])[CH2:4][CH2:5][CH2:6][NH:7][C:8]([O:10][CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[N:18]([CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH3:36])[CH:19]=[O:20])=[O:9]>C(OCC)(=O)C>[ClH:1].[CH3:37][N:3]([CH3:2])[CH2:4][CH2:5][CH2:6][NH:7][C:8]([O:10][CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[N:18]([CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH3:36])[CH:19]=[O:20])=[O:9]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 53674416HCID 53674416, compound

Product 1

HCID 88176311HCID 88176311, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent2×

Procedure

4N Hydrochloric acid--ethyl acetate solution (0.12 ml) was added to a solution of [2-[[N-[3-(dimethylamino)propyl]carbamoyloxy]methyl]phenyl]-N-hexadecylformamide (0.20 g) in ethyl acetate (2 ml) at room temperature. After being stirred for 15 minutes, the reaction mixture was concentrated. The residue was recrystallized from ethyl acetate, thereby yielding 0.19 g of the aimed compound as white crystals.

Workup

  1. concentrationthe reaction mixture was concentrated
  2. customThe residue was recrystallized from ethyl acetate

Sources & evidence

ORD record
ord-1b18de1d3d304eeeb0115eb2810995b4
Source dataset
uspto-grants-2000_09
Patent number
US06114325

Reaction notes

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