Hydrogen chloride-ethyl acetate → HCID 88176606, compound

HRID 1952800Notes

Reaction equation

HRID 1952800 reaction equation
C(OC(=O)C)C.[ClH:7].[CH3:8][N:9]([CH3:44])[CH2:10][CH2:11][NH:12][C:13]([O:15][CH2:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=1[N:23]([CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH3:43])[CH:24]=[O:25])=[O:14]>C(OCC)(=O)C>[ClH:7].[CH3:8][N:9]([CH3:44])[CH2:10][CH2:11][NH:12][C:13]([O:15][CH2:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=1[N:23]([CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH3:43])[CH:24]=[O:25])=[O:14]

Participants

4

Reactant 2

HCID 21866389Hydrogen chloride-ethyl acetateHCID 54034629HCID 54034629, compound

Product 1

HCID 88176606HCID 88176606, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

4N Hydrochloric acid - ethyl acetate solution (0.12 ml) was added to a solution of [2-[[N-[2-(dimethylamino)ethyl]carbamoyloxy]methyl]phenyl]-N-octadecylformamide (0.200 g) in ethyl acetate (2 ml) at room temperature. After being stirred for 15 minutes, the reaction mixture was concentrated. The residue was recrystallized from ethyl acetate-ethanol mixed solvent, thereby yielding 0.205 g of the aimed compound as white crystals.

Workup

  1. concentrationthe reaction mixture was concentrated
  2. customThe residue was recrystallized from ethyl acetate-ethanol mixed solvent

Sources & evidence

ORD record
ord-c2e4ea6324f243b0a3b5aa9f8b16af48
Source dataset
uspto-grants-2000_09
Patent number
US06114325

Reaction notes

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