Hydrochloric Acid → HCID 88178190, compound

HRID 1952805Notes

Reaction equation

HRID 1952805 reaction equation
[ClH:1].[NH2:2][CH2:3][CH2:4][NH:5][C:6]([O:8][CH2:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[N:16]([CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH3:36])[CH:17]=[O:18])=[O:7]>C(OCC)(=O)C.C(O)C>[ClH:1].[NH2:2][CH2:3][CH2:4][NH:5][C:6]([O:8][CH2:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[N:16]([CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH3:36])[CH:17]=[O:18])=[O:7]

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 53812588HCID 53812588, compound

Product 1

HCID 88178190HCID 88178190, compound

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 8857Ethyl AcetateSolvent2×

Procedure

4N Hydrochloric acid--ethyl acetate solution (0.30 ml) was added to a solution of [2-[[N-(2-Aminoethyl)carbamoyloxy]methyl]phenyl]-N-octadecylformamide (0.33 g) in a mixture of ethyl acetate (10 ml) and ethanol (2 ml) at room temperature. After being stirred for 10 minutes, the reaction mixture was concentrated. The residue was recrystallized from ethyl acetate-ethanol mixed solvent, thereby yielding 0.30 g of the aimed compound as white crystals.

Workup

  1. concentrationthe reaction mixture was concentrated
  2. customThe residue was recrystallized from ethyl acetate-ethanol mixed solvent

Sources & evidence

ORD record
ord-e88341e5e6134036b7a41ecf993657f5
Source dataset
uspto-grants-2000_09
Patent number
US06114325

Reaction notes

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