Hydrochloric Acid → HCID 23299432, compound

HRID 1952812Notes

Reaction equation

HRID 1952812 reaction equation
[ClH:1].[CH2:2]([NH:20][C:21]([C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][C:24]=1[CH2:29][O:30][C:31]([N:33]1[CH2:38][CH2:37][N:36]([CH3:39])[CH2:35][CH2:34]1)=[O:32])=[O:22])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19]>C(OCC)(=O)C>[ClH:1].[CH2:2]([NH:20][C:21]([C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][C:24]=1[CH2:29][O:30][C:31]([N:33]1[CH2:38][CH2:37][N:36]([CH3:39])[CH2:35][CH2:34]1)=[O:32])=[O:22])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 15484866HCID 15484866, compound

Product 1

HCID 23299432HCID 23299432, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent2×

Procedure

4N Hydrochloric acid--ethyl acetate solution (0.28 ml) was added to a solution of [2-(N-octadecylcarbamoyl)phenyl]methyl-4-methylpiperazinecarboxylate (0.30 g) in ethyl acetate (4 ml) at room temperature. After being stirred for 10 minutes, the reaction mixture was concentrated. The residue was recrystallized from ethyl acetate-ethanol mixed solvent, thereby yielding 0.32 g of the aimed compound as white solid.

Workup

  1. concentrationthe reaction mixture was concentrated
  2. customThe residue was recrystallized from ethyl acetate-ethanol mixed solvent

Sources & evidence

ORD record
ord-a5904480f8ab4dd49da2a2ceb0be2f3f
Source dataset
uspto-grants-2000_09
Patent number
US06114325

Reaction notes

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